Product Name: | UC-514321 |
Catalog Number: | M29859 |
CAS Number: | 299420-83-0 |
Formula: | C26H35NO5 |
Molecular Weight: | 441.56 |
Form: | Solid |
Solubility: | Ethanol 50 mg/mL (ultrasonic); DMSO 25 mg/mL (ultrasonic) |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: |
QC Standard: | ≥99.0% |
H-NMR: | Consistent with structure |
Description: | UC-514321, a structural analog of NSC370284 with higher activity, directly targets STAT3/5 and represses TET1 expression, but not TET2 or TET3. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |