Certificate of Analysis

 

Product Name: Tris(2-carboxyethyl)phosphine hydrochloride
Catalog Number: M7529
CAS Number: 51805-45-9

Physical and Chemical Properties
Formula: C9H15O6P·HCl
Molecular Weight: 286.65
Solubility: 45 mg/mL in water
Storage: 2-8°C, dry, protect from light, sealed
Chemical Structure: Tris(2-carboxyethyl)phosphine hydrochloride Structure
Analytical Data
QC Standard: >98.0%
H-NMR: Consistent with structure
Product Information
Description: Disufide crosslinks of cystines in proteins can be reduced to cysteine residues by TCEP (tris-(2-carboxyethyl)phosphine). Unlike DTT (dithiothreitol), TCEP does not contain thiols and therefore usually does not need to be removed prior to thiol modification.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.