Certificate of Analysis

 

Catalog Number: M6241
Product Name: Tenovin 6 Hydrochloride
CAS Number: 1011301-29-3

Physical and Chemical Properties
Formula: C25H35ClN4O2S
Molecular Weight: 491.09
Solubility: 49 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: Tenovin 6 Hydrochloride Structure
Analytical Data
HPLC: Shows Min 99.66% purity
H-NMR: Consistent with structure
Product Information
Description: Tenovin-6 Hydrochloride is a water soluble inhibitor of SIRT1 and SIRT2, slightly inhibits HDAC8, and is also a potent activator of p53, with IC50s of 21 μM, 10 μM, 67 μM for SirT1, SirT2, and SirT3, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.