Certificate of Analysis

 

Catalog Number: M1827
Product Name: Sorafenib Tosylate
CAS Number: 475207-59-1

Physical and Chemical Properties
Formula: C21H16ClF3N4O3.C7H8O3S
Molecular Weight: 637.03
Solubility: DMSO 30 mg/mL
Storage: at -20°C
Chemical Structure: Sorafenib Tosylate Structure
Analytical Data
HPLC: Shows Min 100.0% purity
H-NMR: Consistent with structure
Product Information
Description: Sorafenib (BAY 43-9006) Tosylate is an orally active multikinase inhibitor of tyrosine protein kinases VEGFR/PDGFR and RAF/MEK/ERK with IC50 values of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.