|Product Name:||Sorafenib Tosylate|
|Solubility:||DMSO ≥100 mg/mL|
|Long-term Storage:||at -20°C|
|HPLC:||Shows Min >99% purity|
|H-NMR:||Consistent with structure|
|Description:||Sorafenib (BAY 43-9006) is an orally active multikinase inhibitor of tyrosine protein kinases VEGFR/PDGFR and RAF/MEK/ERK with IC50 values of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF.|
|Stability and Solubility Advice:|| Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.