Certificate of Analysis

 

Product Name: SLM6031434 hydrochloride 
Catalog Number: M29002
CAS Number: 1897379-34-8

Physical and Chemical Properties
Formula: C22H31ClF3N5O2
Molecular Weight: 489.96
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: SLM6031434 hydrochloride  Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.