Certificate of Analysis


Catalog Number: M1779
Product Name: SGI-1776
CAS Number: 1025065-69-3

Physical and Chemical Properties
Formula: C20H22F3N5O
Molecular Weight: 405.42
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: SGI-1776 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: SGI-1776 is novel small molecule inhibitor of PIM kinase activity with IC50 of 7 ± 1.8, 363 ± 27.6 and 69 ± 9.2 nM for Pim-1, Pim-2, and Pim-3, respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.