Catalog Number: | M2277 |
Product Name: | Semagacestat |
CAS Number: | 425386-60-3 |
Formula: | C19H27N3O4 |
Molecular Weight: | 361.44 |
Solubility: | DMSO 50 mg/mL |
Storage: | at -20°C |
Chemical Structure: | ![]() |
HPLC: | Shows Min >99% purity |
H-NMR: | Consistent with structure |
Description: | Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, respectively. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |