Certificate of Analysis
| Product Name: | SEL120-34A HCl |
| Catalog Number: | M28663 |
| CAS Number: | 1609452-30-3 |
Physical and Chemical Properties
| Formula: | C15H18Br2N4.HCl |
| Molecular Weight: | 450.6 |
| Form: | Solid |
| Solubility: | Water 45 mg/mL; DMSO 10 mg/mL (ultrasonic and warming) |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SEL120-34A HCl is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC50s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |