Certificate of Analysis

 

Product Name: SAR407899 hydrochloride
Catalog Number: M13732
CAS Number: 923262-96-8

Physical and Chemical Properties
Molecular Weight: 280.75
Solubility: Water 50 mg/mL; DMSO 25 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: SAR407899 hydrochloride Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.