|Solubility:||54 mg/mL in DMSO|
|Long-term Storage:||at -20°C|
|HPLC:||Shows Min 100.00% purity|
|H-NMR:||Consistent with structure|
|Description:||Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.|
|Stability and Solubility Advice:|| Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.