Certificate of Analysis


Catalog Number: M2995
Product Name: Salinosporamide A
CAS Number: 437742-34-2

Physical and Chemical Properties
Formula: C15H20ClNO4
Molecular Weight: 313.78
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: Salinosporamide A  Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Salinosporamide A (NPI-0052, Marizomib) is a novel marine derived proteasome inhibitor which inhibits CT-L, C-L, and T-L proteasome activities in human erythrocyte-derived 20S proteasomes with EC50 of 3.5 nM, 430 nM, 28 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.