Product Name: | SAG dihydrochloride |
Catalog Number: | M14929 |
Molecular Weight: | 562.98 |
Solubility: | Water 90 mg/mL; DMSO 33.33 mg/mL |
Storage: | 2-8°C, dry, sealed |
Chemical Structure: |
QC Standard: | >99% |
Description: | SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine inhibition of Smo. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |