Certificate of Analysis

 

Catalog Number: M3030
Product Name: S-Ruxolitinib
CAS Number: 941685-37-6

Physical and Chemical Properties
Formula: C17H18N6
Molecular Weight: 306.37
Solubility: DMSO 50 mg/mL
Long-term Storage: at -20℃
Chemical Structure: S-Ruxolitinib  Structure
Analytical Data
HPLC: Shows Min 100.00% purity
H-NMR: Consistent with structure
Product Information
Description: S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.