Certificate of Analysis
| Product Name: | Ruboxistaurin |
| Catalog Number: | M10770 |
| CAS Number: | 169939-94-0 |
Physical and Chemical Properties
| Formula: | C28H28N4O3 |
| Molecular Weight: | 468.55 |
| Form: | Solid |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Ruboxistaurin (LY333531) is an orally active, selective PKC beta inhibitor (Ki=2 nM), ruboxistaurin exhibits ATP-dependent competitive inhibition of PKC beta I, which IC50 4.7 nM. Ruboxistaurin for PKC beta II IC50 5.9 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |