Certificate of Analysis


Catalog Number: M5135
Product Name: Ro-46-2005
CAS Number: 150725-87-4

Physical and Chemical Properties
Formula: C23H27N3O6S
Molecular Weight: 473.54
Solubility: DMSO 28mg/mL
Long-term Storage: at -20°C
Chemical Structure: Ro-46-2005 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.