Certificate of Analysis
| Product Name: | Ro-46-2005 |
| Catalog Number: | M5135 |
| CAS Number: | 150725-87-4 |
Physical and Chemical Properties
| Formula: | C23H27N3O6S |
| Molecular Weight: | 473.54 |
| Solubility: | DMSO 28mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.10% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |