Certificate of Analysis

 

Product Name: Rivastigmine
Catalog Number: M10928
CAS Number: 123441-03-2

Physical and Chemical Properties
Formula: C14H22N2O2
Molecular Weight: 250.34
Solubility: DMSO ≥ 40 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Rivastigmine Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Rivastigmine (S-Rivastigmine) is an orally active, potent cholinesterase (ChE) inhibitor that inhibits butyrylcholinesterase (BChE) and acetylcholinesterase (AChE),IC50 0.037 μM and 4.15 μM, respectively. Rivastigmine can pass through the blood-brain barrier (BBB). Rivastigmine is an parasympathetic or cholinergic agent used to study dementia caused by mild to moderate Alzheimer's and Parkinson's disease.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.