Certificate of Analysis

 

Product Name: RG7800
Catalog Number: M11535
CAS Number: 1449598-06-4

Physical and Chemical Properties
Formula: C24H28N6O
Molecular Weight: 416.52
Solubility: DMSO:1.4 mg/mL
Storage: 4-8°C
Chemical Structure: RG7800 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: RG7800 is a small molecule SMN2 splicing modifier. RG7800 has the potential to be used in spinal muscular atrophy. RG7800 corrects selective splicing of the human SMN2 gene in the brain of a transgenic SMA model mouse, leading to an increase in SMN protein in the brain.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.