Certificate of Analysis

 

Product Name: RET-IN-22
Catalog Number: M43521
CAS Number: 2918281-79-3

Physical and Chemical Properties
Formula: C29H31F3N6O4
Molecular Weight: 584.59
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: RET-IN-22 Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: RET-IN-22 is a potent, selective and orally active RET inhibitor with an IC50 of 20.9 nM and 18.3 nM for wild-type RET and RET-V804M, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.