Certificate of Analysis

 

Product Name: Ravoxertinib hydrochloride
Catalog Number: M14153
CAS Number: 2070009-58-2

Physical and Chemical Properties
Molecular Weight: 477.32
Solubility: DMSO 90 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: Ravoxertinib hydrochloride Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Ravoxertinib hydrochloride (GDC-0994 hydrochloride) is an orally bioavailable inhibitor selective for ERK kinase activity with IC50 of 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.