Certificate of Analysis

 

Product Name: (R)-Lisofylline
Catalog Number: M27603
CAS Number: 100324-81-0

Physical and Chemical Properties
Formula: C13H20N4O3
Molecular Weight: 280.32
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: -20°C, sealed
Chemical Structure: (R)-Lisofylline Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: (R)-Lisofylline ((R)-Lisophylline) is a (R)-enantiomer of the metabolite of Pentoxifylline with anti-inflammatory properties. (R)-Lisofylline is a lysophosphatidic acid acyltransferase inhibitor with an IC50 of 0.6 µM and interrupts IL-12 signaling-mediated STAT4 activation. (R)-Lisofylline has the potential for type 1 diabetes, autoimmune disorders research.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.