Certificate of Analysis

 

Product Name: (R)-GNE-140
Catalog Number: M10771
CAS Number: 2003234-63-5

Physical and Chemical Properties
Formula: C25H23ClN2O3S2
Molecular Weight: 499.04
Form: Solid
Solubility: DMSO ≥ 20 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: (R)-GNE-140  Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: (R)-GNE-140 is a selective inhibitor of LDHA and LDHB with IC50 of 3 nM and 5 nM, respectively. (R)-GNE-140 is 18 times more potent than its S-type isomer.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.