Certificate of Analysis


Catalog Number: M1767
Product Name: R-406
CAS Number: 841290-80-0

Physical and Chemical Properties
Formula: C22H23FN6O5
Molecular Weight: 470.45
Solubility: DMSO ≥29 mg/mL
Long-term Storage: at -20°C
Chemical Structure: R-406 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: R406 is an orally bioavailable and selective inhibitor of spleen tyrosine kinase (Syk) with the IC50 of 41nM and Ki value of 30 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.