Certificate of Analysis

 

Product Name: Polyinosinic acid: polycytidylic acid (poly I:C)
Catalog Number: M5062
CAS Number: 24939-03-5

Physical and Chemical Properties
Formula: C19H27N7O16P2
Molecular Weight: 671.40
Solubility: Water 30 mg/mL
Storage: -20°C, dry, sealed
Chemical Structure: Polyinosinic acid: polycytidylic acid (poly I:C) Structure
Analytical Data
QC Standard: 99.0%
H-NMR: Consistent with structure
Product Information
Description: Polyinosinic acid: polycytidylic acid (poly I:C) is a synthetic polyinosinic-polycytidylic acid double-stranded RNA. Polyinosinic-polycytidylic acid (Poly (I:C)) is an agonist of toll-like receptor (TLR)-3. Polyinosinic-polycytidylic acid has protective effects against cerebral ischemia/reperfusion (I/R) injury and can be used as vaccine adjuvant to enhance innate and adaptive immune responses.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.