Certificate of Analysis


Catalog Number: M1774
Product Name: PLX-4720
CAS Number: 918505-84-7

Physical and Chemical Properties
Formula: C17H14ClF2N3O3S
Molecular Weight: 413.83
Solubility: DMSO ≥81 mg/mL
Long-term Storage: at -20°C
Chemical Structure: PLX-4720 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: PLX-4720 is a selective BRAFV600E inhibitor with the IC50 values of 160 nM and 130 nM for B-Raf and BRK respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.