|Solubility:||DMSO ≥95 mg/mL|
|Long-term Storage:||at -20°C|
|HPLC:||Shows Min >98% purity|
|H-NMR:||Consistent with structure|
|Description:||PHA-739358 (Danusertib) is a small molecule with low nanomolar activity against all aurora kinases (AKs) with IC50 value of 13 nM for aurora-A and 79 nM for aurora-B respectively.|
|Stability and Solubility Advice:|| Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.