Certificate of Analysis


Catalog Number: M1769
Product Name: PHA-739358
CAS Number: 827318-97-8

Physical and Chemical Properties
Formula: C26H30N6O3
Molecular Weight: 474.55
Solubility: DMSO ≥95 mg/mL
Long-term Storage: at -20°C
Chemical Structure: PHA-739358 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: PHA-739358 (Danusertib) is a small molecule with low nanomolar activity against all aurora kinases (AKs) with IC50 value of 13 nM for aurora-A and 79 nM for aurora-B respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.