Certificate of Analysis


Catalog Number: M5128
Product Name: PFI-2
CAS Number: 1627676-59-8

Physical and Chemical Properties
Formula: C23H25F4N3O3S
Molecular Weight: 499.52
Solubility: DMSO 99 mg/mL;Water 4 mg/mL warmed
Long-term Storage: at -20°C
Chemical Structure: PFI-2 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.