Certificate of Analysis


Catalog Number: M5335
Product Name: PF-4989216
CAS Number: 1276553-09-3

Physical and Chemical Properties
Formula: C18H13FN6OS
Molecular Weight: 380.4
Solubility: 76 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: PF-4989216 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.