Certificate of Analysis

 

Product Name: PF-4136309
Catalog Number: M20822
CAS Number: 857679-55-1

Physical and Chemical Properties
Formula: C29H31F3N6O3
Molecular Weight: 568.59
Solubility: DMSO 100 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: PF-4136309 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: PF-4136309 (INCB8761, PF-04136309) is a potent, selective, and orally bioavailable CCR2 antagonist with an IC50 of 5.2 nM for human CCR2.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.