Certificate of Analysis


Catalog Number: M3975
Product Name: PF-06463922
CAS Number: 1454846-35-5

Physical and Chemical Properties
Formula: C21H19FN6O2
Molecular Weight: 406.41
Solubility: DMSO 80mg/ml
Long-term Storage: at -20°C
Chemical Structure: PF-06463922 Structure
Analytical Data
HPLC: Shows Min 99.42% purity
H-NMR: Consistent with structure
Product Information
Description: PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitorwith Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.