Certificate of Analysis

 

Product Name: Pamufetinib
Catalog Number: M11224
CAS Number: 1190836-34-0

Physical and Chemical Properties
Formula: C27H23FN4O4S
Molecular Weight: 518.56
Solubility: DMSO ≥ 5 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Pamufetinib Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Pamufetinib (TAS-115) is a highly potent inhibitor of both C-MET and VEGFR, with IC50 of 30 nM and 32 nM against recombinant VEGFR2 and VEGFR, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.