Certificate of Analysis


Catalog Number: M6167
Product Name: Palbociclib
CAS Number: 571190-30-2

Physical and Chemical Properties
Formula: C24H29N7O2
Molecular Weight: 447.53
Solubility: 0.2 mg/mL in DMSO
Storage: at -20°C
Chemical Structure: Palbociclib Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Palbociclib is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.