Certificate of Analysis

 

Product Name: ON123300
Catalog Number: M7557
CAS Number: 1357470-29-1

Physical and Chemical Properties
Formula: C24H27N7O
Molecular Weight: 429.52
Solubility: 10 mM in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: ON123300  Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: ON123300 is a potent inhibitor of CDK4, with an IC50 of 3.8 nM, with little inhibitory activity against CDKs 1,2,5 and 8.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.