Certificate of Analysis

 

Product Name: Roginolisib hemifumarate
Catalog Number: M28709
CAS Number: 1621688-31-0

Physical and Chemical Properties
Formula: C26H27FN4O5S.1/2C4H4O4
Molecular Weight: 584.62
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: 4°C, dry, sealed
Chemical Structure: Roginolisib hemifumarate Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Roginolisib (MSC2360844) hemifumarate is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib hemifumarate shows highly selective against a panel of 278 additional kinases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.