Certificate of Analysis
| Product Name: | MM-589 TFA |
| Catalog Number: | M29447 |
| CAS Number: | 2253167-09-6 |
Physical and Chemical Properties
| Formula: | C30H45F3N8O7 |
| Molecular Weight: | 686.72 |
| Form: | Solid |
| Solubility: | DMSO 25 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | -20°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | MM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interaction. MM-589 binds to WDR5 with an IC50 of 0.90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC50 of 12.7 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |