Certificate of Analysis

 

Catalog Number: M2856
Product Name: MK-8745
CAS Number: 885325-71-3

Physical and Chemical Properties
Formula: C20H19ClFN5OS
Molecular Weight: 431.91
Solubility: DMSO 70 mg/mL
Long-term Storage: at -20℃
Chemical Structure: MK-8745 Structure
Analytical Data
HPLC: Shows Min >99% purity
H-NMR: Consistent with structure
Product Information
Description: MK-8745 is a potent and selective Aurora A inhibitor with IC50 of 0.6 nM, more than 450-fold selectivity for Aurora A over Aurora B.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.