Certificate of Analysis


Catalog Number: M2120
Product Name: MK-0752
CAS Number: 471905-41-6

Physical and Chemical Properties
Formula: C21H21ClF2O4S
Molecular Weight: 442.9
Solubility: DMSO 80 mg/mL, Ethanol 40 mg/mL
Long-term Storage: at -20°C
Chemical Structure: MK-0752 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: MK-0752 is a potent, oral inhibitor of γ-secretase with IC50 of 5 nM in human SH-SY5Y cells.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.