Certificate of Analysis

 

Product Name: Mizagliflozin
Catalog Number: M30450
CAS Number: 666843-10-3

Physical and Chemical Properties
Formula: C28H44N4O8
Molecular Weight: 564.67
Form: Solid
Solubility: Water ≥ 100 mg/mL (ultrasonic)
Storage: 4°C, protect from light
Chemical Structure: Mizagliflozin Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.