Certificate of Analysis

 

Product Name: Minocycline hydrochloride
Catalog Number: M2854
CAS Number: 13614-98-7

Physical and Chemical Properties
Formula: C23H27N3O7.HCl
Molecular Weight: 493.94
Solubility: Water 9 mg/mL; DMSO 15 mg/mL
Storage: -20°C, dry, sealed
Chemical Structure: Minocycline hydrochloride Structure
Analytical Data
QC Standard: 99.66%
H-NMR: Consistent with structure
Product Information
Description: Minocycline hydrochloride is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.