Certificate of Analysis

 

Product Name: M-3258
Catalog Number: M10767
CAS Number: 2285330-15-4

Physical and Chemical Properties
Formula: C17H20BNO5
Molecular Weight: 329.16
Solubility: DMSO ≥ 200 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: M-3258 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: M3258 is an oral bioavailable, potent, reversible, and highly selective immunoproteasome subunit LMP7 (β5i) inhibitor. M3258 for LMP7 IC50 is 3.6 nM in cells IC50 3.4 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.