Certificate of Analysis

 

Product Name: LOXO-101 sulfate
Catalog Number: M6211
CAS Number: 1223405-08-0

Physical and Chemical Properties
Formula: C21H22F2N6O2.H2O4S
Molecular Weight: 526.51
Solubility: DMSO 50 mg/mL (Need ultrasonic)
Storage: 4°C, dry, sealed
Chemical Structure: LOXO-101 sulfate Structure
Analytical Data
QC Standard: >98.5%
H-NMR: Consistent with structure
Product Information
Description: LOXO-101 sulfate is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.