Certificate of Analysis


Catalog Number: M2307
Product Name: Lonafarnib
CAS Number: 193275-84-2

Physical and Chemical Properties
Formula: C27H31Br2ClN4O2
Molecular Weight: 638.82
Solubility: DMSO 100 mg/mL, Ethanol 100 mg/mL
Long-term Storage: at -20°C
Chemical Structure: Lonafarnib Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.