Certificate of Analysis

 

Product Name: LDC4297
Catalog Number: M5263
CAS Number: 1453834-21-3

Physical and Chemical Properties
Formula: C23H28N8O
Molecular Weight: 432.52
Solubility: 86 mg/mL in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: LDC4297 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: LDC4297 is a novel CDK7 inhibitor (IC50=0.13±0.06 nM for CDK7 versus IC50s between 10 nM and 10,000 nM for all other analyzed CDKs).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.