Certificate of Analysis

 

Product Name: JSH-23
Catalog Number: M2786
CAS Number: 749886-87-1

Physical and Chemical Properties
Formula: C16H20N2
Molecular Weight: 240.34
Solubility: DMSO 28 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: JSH-23 Structure
Analytical Data
QC Standard: 99.00%
H-NMR: Consistent with structure
Product Information
Description: Jsh-23 is a NF-κB inhibitor, inhibited NF-κB transcriptional activity in lipopolysaccharid-stimulated macrophages RAW 264.7 with IC50 of 7.1 μM. Jsh-23 inhibited the nuclear translocation of NF-κB P65 without affecting the degradation of IκBα.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.