Certificate of Analysis


Catalog Number: M1800
Product Name: JNJ-7706621
CAS Number: 443797-96-4

Physical and Chemical Properties
Formula: C15H12F2N6O3S
Molecular Weight: 394.36
Solubility: DMSO
Long-term Storage: at -20°C
Chemical Structure: JNJ-7706621 Structure
Analytical Data
HPLC: Shows Min 98.23% purity
H-NMR: Consistent with structure
Product Information
Description: JNJ-7706621 is a dual cell cycle inhibitor with activity against cyclin-dependent kinases (CDK1, 2, 3, 6) with an IC50 of 3-175 nM and Aurora kinases (A and B) with an IC50 of 11-15 nM respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.