Certificate of Analysis
| Product Name: | JNJ-7706621 |
| Catalog Number: | M1800 |
| CAS Number: | 443797-96-4 |
Physical and Chemical Properties
| Formula: | C15H12F2N6O3S |
| Molecular Weight: | 394.36 |
| Solubility: | DMSO 69 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | JNJ-7706621 is a dual cell cycle inhibitor with activity against cyclin-dependent kinases (CDK1, 2, 3, 6) with an IC50 of 3-175 nM and Aurora kinases (A and B) with an IC50 of 11-15 nM respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |