Certificate of Analysis

 

Product Name: JNJ-42041935
Catalog Number: M8963
CAS Number: 1193383-09-3

Physical and Chemical Properties
Formula: C12H6ClF3N4O3
Molecular Weight: 346.65
Solubility: DMSO: ≥ 30 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: JNJ-42041935 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: JNJ-42041935 is a potent, competitive, reversible, and selective inhibitor of PHD with pKi values of 7.91±0.04, 7.29 ±0.05, and 7.65±0.09 for PHD1, PHD2, and PHD3, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.