Certificate of Analysis

 

Product Name: JIB-04
Catalog Number: M2275
CAS Number: 199596-05-9

Physical and Chemical Properties
Formula: C17H13ClN4
Molecular Weight: 308.76
Solubility: DMSO 10 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: JIB-04 Structure
Analytical Data
QC Standard: 99.79%
H-NMR: Consistent with structure
Product Information
Description: JIB-04 is a selective inhibitor of Jumonji histone demethylase with IC50 values of 230, 340, 435, 445, 855 and 1100 nM for JARID1A, JMJD2E, JMJD2B, JMJD2A, JMJD3 and JMJD2C respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.