Product Name: | Icotinib Hydrochloride |
Catalog Number: | M4937 |
CAS Number: | 1204313-51-8 |
Formula: | C22H22ClN3O4 |
Molecular Weight: | 427.88 |
Form: | Solid |
Solubility: | 10 mM in DMSO |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: |
QC Standard: | >98% |
H-NMR: | Consistent with structure |
Description: | Icotinib Hcl(BPI-2009H) is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC(50) of 5 nM, including it's mutants of EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R). |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |