Certificate of Analysis
| Product Name: | Huwentoxin IV TFA |
| Catalog Number: | M10458 |
| CAS Number: | 526224-73-7 (free base) |
Physical and Chemical Properties
| Formula: | C176H279F3N52O53S6 |
| Molecular Weight: | 4220.80 |
| Solubility: | Water 1 mg/mL |
| Storage: | -20°C, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Huwentoxin IV TFA is a selective NaV1.7 channel blocker, which preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 μM). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |