Certificate of Analysis

 

Product Name: HPI-4
Catalog Number: M6149
CAS Number: 302803-72-1

Physical and Chemical Properties
Formula: C17H9Cl2N3O2
Molecular Weight: 358.18
Solubility: 61 mg/mL in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: HPI-4 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: HPI-4 (Ciliobrevin A) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.