Certificate of Analysis


Catalog Number: M6149
Product Name: HPI-4
CAS Number: 302803-72-1

Physical and Chemical Properties
Formula: C17H9Cl2N3O2
Molecular Weight: 358.18
Solubility: 71 mg/mL in DMSO
Long-term Storage: at -20°C
Chemical Structure: HPI-4 Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: HPI-4 (Ciliobrevin A) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials at -20°C or below and used within 1 month.