Product Name: | HPI-4 |
Catalog Number: | M6149 |
CAS Number: | 302803-72-1 |
Formula: | C17H9Cl2N3O2 |
Molecular Weight: | 358.18 |
Solubility: | 61 mg/mL in DMSO |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: |
QC Standard: | >98% |
H-NMR: | Consistent with structure |
Description: | HPI-4 (Ciliobrevin A) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |