Certificate of Analysis

 

Product Name: H-1152
Catalog Number: M4938
CAS Number: 451462-58-1

Physical and Chemical Properties
Formula: C16H21N3O2S
Molecular Weight: 319.42
Solubility: 10 mM in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: H-1152 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: H-1152, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.